Eye Disease Research on Leaky Vessels

A new study shows why people living with an eye disease have leaky vessels and harmful swelling in their eyes. The findings could be a stepping-stone to the discovery of more effective treatments for various types of eye disease, including age-related macular degeneration (AMD) and diabetic retinopathy. The researchers report that eye conditions that result in leaky blood vessels result in harmful swelling and progressive vision loss.

"Our findings provide an answer to the questions on how blood vessels leak and show that leakage can be stopped without killing the blood vessels," concludes senior author Lena Claesson-Welsh, Professor at the Department of Immunology, Genetics and Pathology, Uppsala University. "Using this insight, we've begun testing drugs that could selectively block this leak-inducing step in the process. If this approach is effective, it could lead to new treatments that stop leaking without the harmful side effects of existing drugs."

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Scientists identify cause of leakiness in eye diseases

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