
"This study really is a step-change in our understanding of how complement activation drives this major blinding disease," said Professor Simon Clark, a specialist in the regulation of the complement system in health and disease at the University of Manchester. "Up until now, the role played by FHR proteins in disease has only ever been inferred. But now we show a direct link and, more excitingly, become a tangible step closer to identifying a group of potential therapeutic targets to treat this debilitating disease."
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"International team delivers research breakthrough for leading cause of blindness"